The Kolkata Knight Riders (KKR) defeated the defending champions Chennai Super Kings (CSK) in the opening game of the 2022 Indian Premier League (IPL). The match was played in the Wankhede Stadium in Mumbai. Umesh Yadav was adjudged to be the Man of the Match.
| CHENNAI SUPER KINGS | 131/5 (20 OVERS) |
| MS DHONI 50* (38) | UMESH YADAV 4-0-20-2 |
| ROBIN UTHAPPA 28 (21) | VARUN CHAKRAVARTHY 4-0-23-1 |
| RAVINDRA JADEJA 26* (28) | ANDRE RUSSELL 4-0-38-1 |
| AMBATI RAYUDU 15 (17) | SUNIL NARINE 4-0-15-0 |
| KOLKATA KNIGHT RIDERS | 133/4 (18.3 OVERS) |
| AJINKYA RAHANE 44 (34) | DWAYNE BRAVO 4-0-20-3 |
| SAM BILLINGS 25 (22) | MITCHELL SANTNER 4-0-31-1 |
|
NITISH RANA 21 (17) |
RAVINDRA JADEJA 4-0-25-0 |
| SHREYAS IYER 20* (19) | ADAM MILNE 2.3-0-19-0 |
