The Mumbai Indians (MI) defeated the Gujarat Titans (GT) in the fifty-first game of the 2022 Indian Premier League (IPL). The match was played in the Brabourne Stadium in Mumbai. Tim David was adjudged to be the Man of the Match.
| MUMBAI INDIANS | 177/6 (20 OVERS) |
| ISHAN KISHAN 45 (29) | RASHID KHAN 4-0-24-2 |
| TIM DAVID 44* (21) | PRADEEP SANGWAN 3-0-23-1 |
| ROHIT SHARMA 43 (28) | LOCKIE FERGUSON 4-0-34-1 |
| TILAK VARMA 21 (16) | ALZARRI JOSEPH 4-0-41-1 |
| GUJARAT TITANS | 172/5 (20 OVERS) |
| WRIDDHIMAN SAHA 55 (40) | MURUGAN ASHWIN 4-0-29-2 |
| SHUBMAN GILL 52 (36) | KIERON POLLARD 2-0-13-1 |
| HARDIK PANDYA 24 (14) | DANIEL SAMS 3-0-18-0 |
| DAVID MILLER 19* (14) | KUMAR KARTIKEYA 3-0-29-0 |
