Concerns about illness or inflation aren’t stopping Americans from hitting the roads and airports this holiday season. But a massive winter storm might.

Forecasters predict an onslaught of heavy snow, ice, flooding and powerful winds from Thursday to Saturday in a broad swath of the country, from the Plains and Midwest to the East Coast. A surge of Arctic air will follow. The Christmas weekend could be the coldest in decades.

The National Weather Service said Wednesday the storm was so large and encompassing that around 190 million people are currently under some type of winter weather advisory.