The 28th Screen Actors Guild Awards will kick off with a “Hamilton” reunion, feature a lifetime achievement award for Helen Mirren and, maybe, supply a preview of the upcoming Academy Awards.

The SAG Awards, taking place at Barker Hangar in Santa Monica, California, begin at 8 p.m. EST Sunday and air on both TNT and TBS. (The show will also be available to stream Monday on HBO Max.) After the January Golden Globes were a non-event, the Screen Actors Guild Awards will be Hollywood’s first major, televised, in-person award show — complete with a red carpet and teary-eyed speeches — this year.

While the Academy Awards aren’t mandating vaccination for presenters (just attendees), it’s required for the SAG Awards, which are voted on by the Hollywood actors’ guild SAG-AFTRA. One actor in the cast of the Paramount series “Yellowstone,” Forrie J. Smith, has said he won’t attend because he isn’t vaccinated.

“Hamilton” trio Lin-Manuel Miranda, Leslie Odom Jr. and Daveed Diggs will open the ceremony. Kate Winslet is to present the actors’ lifetime achievement award to Mirren, a five-time SAG Award winner.