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Study finds lower risk of breast cancer from sun exposure


Nepalnews
2022 Jan 08, 13:51,

A new study by the University of Buffalo and the University of Puerto Rico has found that there is a lower risk of breast cancer in Puerto Rico because of greater sun exposure.

The research has been published in the 'Cancer Epidemiology, Biomarkers & Prevention Journal'.

Researchers used a chromameter to compare skin pigmentation in unexposed and exposed skin in 307 cases and 328 controls. The difference in skin pigmentation provided an estimate of usual sun exposure.

"This study was unique in that it was of Puerto Rican women, which allowed for us to look at this association in a population with a wide range of skin colour and with year-round high sun exposure," said study senior author Jo L. Freudenheim, a SUNY Distinguished Professor in the Department of Epidemiology and Environmental Health in UB's School of Public Health and Health Professions.

There is some, albeit inconsistent, evidence that sun exposure is associated with a lower risk of breast cancer. There are a number of reasons that may explain this finding, said Freudenheim.

"One step in the internal production of vitamin D occurs when skin is exposed to sun," she said.

"Sun exposure also affects the body in a number of other helpful ways, with effects on inflammation, obesity, and circadian rhythms. While recent recommendations have been to limit sun exposure to prevent skin cancer, there may also be a benefit to some sun exposure, especially exposure without sunburn," she added.

The previous studies on sun exposure and breast cancer have been conducted in places that experience seasonal variation in ultraviolet radiation, including periods of low to no exposure. In Puerto Rico, however, there is no significant seasonal fluctuation, with the potential for continuous exposure to high UV radiation for those who spend time outdoors.

"The study provided consistent results across different parameters," said paper's first author Cruz Nazario, PhD, an epidemiology professor at the University of Puerto Rico.

"Breast cancer risk was lower for women with the highest accumulated sun exposure. Similarly, the risk was lower independent of estrogen receptor status, and it was even lower among participants with darker skin colour," Nazario added.

The study was conducted as part of a long-standing collaboration UB has had with the University of Puerto Rico.

Co-authors on the paper included Rosa V. Rosario-Rosado, University of Puerto Rico; Michelle Schelske-Santos, PhD, University of Puerto Rico Rio Piedras; Imar Mansilla-Rivera, PhD, University of Puerto Rico; Farah A. Ramirez-Marrero, PhD, University of Puerto Rico Rio Piedras; Jing Nie, PhD, University at Buffalo; Paola Piovanetti-Fiol, University of Puerto Rico; and Johan Hernandez-Santiago, University of Puerto Rico.

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