Assessing the situation the Ministry of Health and Population (MoHP) has recommended citizens to wear full sleeves clothes, use mosquito nets while sleeping and avoid the store of water in public places.

Dengue emerged in Nepal in the form of Dengue Fever (DF), Dengue Hemorrhagic Fever (DHF) and Dengue Shock Syndrome (DSS). The earliest case, according to MoHP, was detected in 2005. Dengue cases have continued to be detected since then and have resulted in several outbreaks throughout the years. The most affected districts remain to be Chitwan, Kanchanpur, Kailali, Banke, Bardiya, Dang, Kapilvastu, Parsa, Rupandehi, Rautahat, Sarlahi, Saptari and Jhapa, which indicating a spread throughout the country. The entomological surveillance conducted by the Epidemiology and disease control division of Nepal, during the year 2006-2010, has shown dengue spreads through local transmission in Nepal.

Recent study, published in the National Library of Medicine has shown a five time increase in dengue cases in Nepal, from 2016 to 2018. Alarmingly, the studies have shown a trend of dengue disease expanding towards the lowland areas of Nepal to higher elevations, in recent years.